<?xml version="1.0" encoding="UTF-8"?>
<sbml level="2" version="4" xmlns="http://www.sbml.org/sbml/level2/version4">
    <model id="EnzymaticReaction">
        <listOfUnitDefinitions>
            <unitDefinition id="per_second">
                <listOfUnits>
                    <unit kind="second" exponent="-1"/>
                </listOfUnits>
            </unitDefinition>
            <unitDefinition id="litre_per_mole_per_second">
                <listOfUnits>
                    <unit kind="mole"   exponent="-1"/>
                    <unit kind="litre"  exponent="1"/>
                    <unit kind="second" exponent="-1"/>
                </listOfUnits>
            </unitDefinition>
        </listOfUnitDefinitions>
        <listOfCompartments>
            <compartment id="cytosol" size="1e-14"/>
        </listOfCompartments>
        <listOfSpecies>
            <species compartment="cytosol" id="ES" initialAmount="0"     name="ES"/>
            <species compartment="cytosol" id="P"  initialAmount="0"     name="P"/>
            <species compartment="cytosol" id="S"  initialAmount="1e-20" name="S"/>
            <species compartment="cytosol" id="E"  initialAmount="5e-21" name="E"/>
        </listOfSpecies>
        <listOfReactions>
            <reaction id="veq">
                <listOfReactants>
                    <speciesReference species="E"/>
                    <speciesReference species="S"/>
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="ES"/>
                </listOfProducts>
                <kineticLaw>
                    <math xmlns="http://www.w3.org/1998/Math/MathML">
                        <apply>
                            <times/>
                            <ci>cytosol</ci>
                            <apply>
                                <minus/>
                                <apply>
                                    <times/>
                                    <ci>kon</ci>
                                    <ci>E</ci>
                                    <ci>S</ci>
                                </apply>
                                <apply>
                                    <times/>
                                    <ci>koff</ci>
                                    <ci>ES</ci>
                                </apply>
                            </apply>
                        </apply>
                    </math>
                    <listOfParameters>
                        <parameter id="kon"  value="1000000" units="litre_per_mole_per_second"/>
                        <parameter id="koff" value="0.2"     units="per_second"/>
                    </listOfParameters>
                </kineticLaw>
            </reaction>
            <reaction id="vcat" reversible="false">
                <listOfReactants>
                    <speciesReference species="ES"/>
                </listOfReactants>
                <listOfProducts>
                    <speciesReference species="E"/>
                    <speciesReference species="P"/>
                </listOfProducts>
                <kineticLaw>
                    <math xmlns="http://www.w3.org/1998/Math/MathML">
                        <apply>
                            <times/>
                            <ci>cytosol</ci>
                            <ci>kcat</ci>
                            <ci>ES</ci>
                        </apply>
                    </math>
                    <listOfParameters>
                        <parameter id="kcat" value="0.1" units="per_second"/>
                    </listOfParameters>
                </kineticLaw>
            </reaction>
        </listOfReactions>
    </model>
</sbml>
